Tuesday, October 4, 2011

Diabetes found to be an independent risk fact for colon and rectal cancers.

According to a study reported in American Journal of Gastroenterology, the researchers from University of California, Berkeley diabetes is an independent risk fact for colon and rectal cancers. A person with diabetes has a 38% higher risk of developing colon cancer compared to other people. Male diabetes patients were found to have a 20% higher risk of developing rectal cancer.

The authors stressed that they took into account variables which might affect the results, such as smoking, obesity and levels of physical activity. They could not point out as to what causes the link between diabetes and colon and rectal cancer.

For more detals, please click on the links below:


Monday, October 3, 2011

Glycated Hemoglobin (HbA1c) levels fail to diagnose Diabetes and Prediabetes in Arab population

According to the Standards of Medical Care in Diabetes 2011, ADA had recently approved the use of HbA1c levels in diagnosing Diabetes (HbA1c ≥ 6.5%) and Prediabetes (HbA1c levels between 5.7-6.4%). But more and more evidence is accumulating that different cut off values (lower) from the ones suggested by  ADA may be needed in different target populations like this study showed that there were very high false negatives in Arabs with the use of the recommended HbA1c levels. Similarly low sensitivities for diagnosing diabetes and prediabetes with HbA1c have been reported in non-Hispanic whites or blacks, Filipino-Americans, Japanese-Americans, and Native Hawaiians. Thus, it would be unwise to jump and use the HbA1c levels for different target populations and the use of traditional OGTT along with FBS is recommended until we are able to come up with different cut off levels for different target populations.

Caution is advised to medical professionals diagnosing Diabetes and Prediabetes using HbA1c cut off values suggested by ADA across the board for all target populations as this might delay the diagnosis of Diabetes and Prediabetes and thus contribute to increased mortality and morbidity resulting from delayed detection of this disease. Please click on the links below.

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