In an exciting new study, a chemist at Syracuse University, Robert Doyle and his team, demonstrated, for the first time, that a critical hormone PYY (Peptide YY) which is a short (36-amino acid) protein released by cells in the ileum and colon in response to feeding.that helps people feel "full" after eating can be delivered into the bloodstream orally.
Doyle's team is working on incorporating B12-PYY in chewing gum or oral tablets in trials and hoping to deliver PYY without being degraded in the GI system to cause appetite suppression in obese individuals.
If they will be successful, PYY-laced gum would be a natural way to help people lose weight in the near future.
Robert Doyle's study was published online in the American Chemical Society's Journal of Medicinal Chemistry. He collaborated on the study with researchers from Murdoch University in Australia.
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Dr. Harish Malik